UTI Clinical Trials and Other Women’s Health Research Opportunities
Have you ever considered participating in research? There are many different types of studies you can join:
- Clinical trials for new medications and prevention methods
- Scientific research that will help improve the understanding of aspects of female health and illness that are critically under-studied
- Online patient surveys aimed at learning more about the patient experience
- Patient interviews to deeply explore how illnesses impact quality of life
Some research opportunities are paid, and all of them help the broader community. Sign up to be notified whenever a new study is added to this page.
Open Research Studies You Can Join
This survey is investigating how people with recurrent and chronic UTI use treatments and supplements intended to prevent symptoms, and how well they work in everyday life. Preventive treatment is usually taken daily. Some people instead take a dose only around a known trigger, such as sexual activity. Very little has been published about how often this happens, who is offered it, or whether people find it easier to manage. The findings will be used to inform what a future clinical trial should test, and to make the case for funding it.
The study is run by Live UTI Free in collaboration with the University of Reading, takes around 15 minutes, and is open to participants worldwide. You do not need to be taking anything to prevent UTIs to take part. Read the participant information sheet here.
You may be eligible to participate if you:
- Are aged 18 years or older, of any gender.
- Experience recurrent or chronic UTI, meaning at least two UTIs in the past 6 months, at least three in the past 12 months, or UTI symptoms that feel continuous and do not fully go away.
- Are able to complete a survey in English.
- Have internet access.
Some questions cover sensitive topics, including sexual activity. You can choose "prefer not to say" on any question.
The trial is currently open at the following hospital:
- Whittington Hospital, London (Prof Rajvinder Khasriya and Dr Kiren Gill)
- Freeman Hospital, Newcastle Upon Tyne (Prof Chris Harding)
The trial is expected to open at the following trial locations within the next few months:
- University College London Hospital, London (Dr Anthony Kupelian)
You may be eligible to participate if you:
- Are a female aged 18 years or older.
- Currently reside in the United Kingdom.
- Experience UTI where symptoms are continuous and have occurred every day for at least 3 months.
Researchers at the Leiden University Center for Infectious Diseases are conducting a study to better understand the impact of UTIs on a global scale, and you can help by joining the study!
This survey aims to understand how people living with urinary tract infections (UTI) feel about themselves and how they think others perceive them. Your experiences will help us understand the impact of the UTIs, and how stigma might play a role.
- Are based anywhere in the world
- Are 18 years or older
- Have experienced at least one UTI in their adulthood
Participation in the study requires completion of a questionnaire, which will take approximately 10 to 15 minutes.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Are aged 16 years or older
- Have experienced:
- Two episodes of symptomatic UTI in the previous 6 months despite treatment with antibiotics, methenamine (antiseptic) or vaginal oestrogen; Or
- At least three episodes of symptomatic UTI treated with antibiotics, in the previous 12 months;
- Are able to receive treatments inside their bladder (intravesical) and take second-line oral antibiotics as prophylaxis (preventative);
- Are willing to adhere to a 12‐month trial protocol.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
Who can participate? Individuals with:
- At least 4 episodes of UTI in the last 12 months
-
UTI where E. coli or K. pneumoniae was identified in at least 3 of these episode
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Currently experiencing, or who have experienced symptoms of a urinary tract infection within the past 12 months
- Or the adult sexual partner of a person experiencing symptoms of a urinary tract infection.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Adolescents aged 14-17 who experience UTIs
- Parents/Caregivers of a child aged 0-17 who experiences UTIs
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Be diagnosed with recurrent UTIs
- Not be in a long-term relationship
- Be aged 18 or older and fluent in English
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Be diagnosed with recurrent UTIs or have a partner who has a diagnosis
- Be in a long-term relationship (including marriage or civil partnerships) for at least 12 months with one or more partner(s)
- Be aged 18 or older and fluent in English
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
Dr Philippe Zimmern and researchers from UT Southwestern Medical are inviting individuals:
- Aged 18-85 years old
- With a documented history of recurrent UTI
- Who are experiencing an acute cystitis episode for which they require antibiotic treatment
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
Inclusion criteria:
- Aged 18-85 years old
- History of recurrent UTI
Exclusion criteria:
- Pregnancy
- Using self-start antibiotics
- Uncontrolled diabetes
- Kidney or liver disease
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
Previous Studies That Are Now Closed
- Are based anywhere in the world
- Are 18 years or older
- Have experience of UTI diagnostics (for themselves or on behalf of an adult or child)
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
You may be eligible to participate if you:
- Are a woman aged 18-75.
- Currently reside in the United States.
- Experience recurrent UTIs* and are otherwise healthy.
- Are not currently pregnant and do not plan to become pregnant in the next 6 months.
- Are willing and able to agree to the requirements of the study.
- Recurrent UTI Symptom Scale – Diary Version
- Recurrent UTI Symptom Scale for Older Adults
- Survey 1: Rate and comment on questionnaire items for clarity and relevance
- Survey 2 (after 28 days): Review your previous answers together with the group summary and median rating obtained from all the expert participants. You will have the opportunity to retain or adjust your ratings.
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
This study has now closed.
- Female participants aged 18-64 years, who:
- Are not pregnant or lactating;
- Have had at least one diagnosed E. coli urinary tract infection (UTI) confirmed by a urine culture test in the past 12 months;
- Do not have a history of complicated UTIs or UTIs that have been linked to physiological or anatomical abnormalities within the urinary tract (see more information about this criterion below);
- Have not previously been administered a vaccine or immunostimulant targeting recurrent UTIs; and
- Are not taking preventative medication and treatments for recurrent UTIs (for example antibiotics, methenamine (Hiprex), D-mannose)*
- Assigned female at birth
- At least 18 years old
- Peri- or postmenopausal
- Willing and able to use the B.Y.M. Microbiome Serum as instructed
- Willing and able to collect and return by post vaginal and labia-perineum swab samples
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Are a woman aged 18-75.
- Currently reside in the United States.
- Experience recurrent UTIs* and are otherwise healthy.
- Are not currently pregnant and do not plan to become pregnant in the next 6 months.
- Are willing and able to agree to the requirements of the study.
This study has now closed.
- A remunerated patient representative role for a la/mUC steering committee.
- A compensated online survey that takes about 30 minutes to complete.
- Participants in Australia, South Korea or Taiwan
- Those with experience of locally advanced or metastatic urothelial carcinoma (la/mUC)
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
This study is being facilitated by Microplate Dx, a company that is currently developing a fast, cost-effective urinary tract infection (UTI) test. The new diagnostic will be used on-site where the patient receives care - for example, at the GP clinic.
We are seeking individuals with lived experience of UTI (personally or as a carer), to help shape the development of this new test, by taking part in one of three focus groups.
The focus group will be held online via a Zoom video call and the anticipated duration is no longer than 90 minutes. Participants will be paid for their time.
- Be aged 18 years or older
- Be based in the UK (including England, Wales, Scotland and Northern Ireland)
- Have experienced at least one UTI in the last 12 months; OR
- Be a carer for an individual who experiences recurrent UTI
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Female participants aged 12 years or older, who:
- Are not pregnant;
- Have no known anatomical abnormalities within the urinary tract; and
- Have experienced signs and symptoms of a urinary tract infection in the last 96 hours
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Control group – healthy participants who do not experience recurrent or chronic UTI
- Cross-sectional – participants who do experience recurrent UTI
- Longitudinal group – participants who do experience recurrent or chronic UTI and are willing to participate for an extended timeframe
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.
- Improve the understanding of recurrent and chronic UTI
- Provide insights into the similarities and differences in patient experiences across different regions
- Highlight the impact on quality of life associated with recurrent and chronic UTI
This study has now closed.
*Recurrent UTI is defined as experiencing 2 or more UTIs in the last 6 months OR 3 or more UTIs in the last 12 months.